Synergistic Effects Between Intrathecal Clonidine and Neostigmine in the Formalin Test
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چکیده
منابع مشابه
Synergistic effects between intrathecal clonidine and neostigmine in the formalin test.
Spinal alpha-2 adrenoceptors and cholinergic receptors are involved in the regulation of acute nociception and the facilitated processing. The aim of this study was to examine the pharmacological effect of an intrathecal alpha-2 agonist and a cholinesterase inhibitor on the facilitated pain model induced by formalin injection and to determine the nature of drug interaction using an isobolograph...
متن کاملAdditive interaction of intrathecal ginsenosides and neostigmine in the rat formalin test
BACKGROUND The authors evaluated the effect of intrathecal mixture of ginsenosides with neostigmine on formalin-induced nociception and made further clear the role of the spinal muscarinic (M) receptors on the activity of ginsenosides. METHODS A catheter was located in the intrathecal space of male Sprague-Dawley rats. Pain was evoked by injection of formalin solution (5%, 50 µl) to the hindp...
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the study reflected in this thesis aims at finding out relationships between critical thinking (ct), and the reading sections of tofel and ielts tests. the study tries to find any relationships between the ct ability of students and their performance on reading tests of tofel and academic ielts. however, no research has ever been conducted to investigate the relationship between ct and the read...
15 صفحه اولAnalgesic Effects of Intrathecal Curcumin in the Rat Formalin Test
BACKGROUND Curcumin has been reported to have anti-inflammatory, antioxidant, antiviral, antifungal, antitumor, and antinociceptive activity when administered systemically. We investigated the analgesic efficacy of intrathecal curcumin in a rat model of inflammatory pain. METHODS Male Sprague Dawley rats were prepared for intrathecal catheterization. Pain was evoked by injection of formalin s...
متن کاملAnalgesic effects of intrathecal neostigmine.
EDITOR: We read about the analgesic effects of intrathecal neostigmine in perianal surgery by Yegin and colleagues with great interest [1]. We agree with them, as we found very similar results, that intrathecal neostigmine increases sensory blockade, motor blockade and increases the incidence of adverse effects such as nausea and vomiting. Hood and colleagues in 1995 suggested that intrathecal ...
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ژورنال
عنوان ژورنال: Journal of Korean Medical Science
سال: 2001
ISSN: 1011-8934,1598-6357
DOI: 10.3346/jkms.2001.16.4.498